Background: The aortic root is an aggregate of various components that connects the left ventricle to the aorta. The most predominant pathologies have been associated with the dilation of the aortic root leading to aneurysms. Aim: This study is designed to measure the role of systemic morbidities such as hypertension, diabetes, and body-mass-index has on the dimension of the aortic root. Materials and methods: Participants were volunteers who were recruited during and after an organized health fair by the Medical Students’ body from …, School of Medicine, …. 169 participants, 62 males, 107 females with ages ranging from 9-84 years agreed to participate by signing the consent after which a questionnaire was administered and a preliminary clinical procedure was used to check for blood pressure, blood glucose, and body mass index. The measurement of the aortic root was carried out by an experienced single investigator using a DUS 5000 ultrasound machine (Miami, Florida, USA) using a low-frequency micro-convex transducer preset to “adult cardiac” with a default frequency of 4MHz. Results and Discussion: Among the participants, 35.03%, 47.80%, and 29.11% had normal blood pressure, blood glucose, and BMI readings, respectively. The chi-squared analysis identified a significant correlation between the diameter of the aortic annulus and body mass index. Diastolic blood pressure also correlated with the diameter of the aortic annulus. Sinus of Valsalva showed no correlation with blood pressure, blood glucose, and body mass index. Conclusion: The disparity in how systemic factor individually correlates with the aortic annulus and the sinus of Valsalva is not clear. The study targets to provide educational concept in this regard.