Abdollahpour

Department of Pediatrics, Iran University of Medical Sciences, Tehran, Iran

Publications

  • Research Article   
    The Effect of Using Prophylactic G-CSF during Chemotherapy on the Outcome of Children with Acute Lymphoblastic Leukemia
    Author(s): Gholamreza Bahoush* and Abdollahpour

    Background: Indications for the use of Granulocyte Colony-Stimulating Factors (G-CSF) have so far been suggested to prevent febrile neutropenia, as well provide support for intensive chemotherapy. However, the long-term consequences of its use in children with Acute Lymphoblastic Leukemia (ALL), especially in the time-sequenced setting, are not yet well understood. Materials and Methods: Children with newly diagnosed acute lymphoblastic leukemia ALL in Ali Asghar Children’s Hospital were randomly assigned to two groups. Patients in both groups underwent chemotherapy according to the ALL IC-BFM 2002 protocol. Patients in Group A were supported in a time-sequenced setting during the second phase of induction and protocol mM and reinduction phase with G-CSF. However, patients in group B received G-CSF only duri.. Read More»

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