Review
Use of Metformin in Pregnant Women with Polycystic Ovarian Syndrome and the Need for Follow-up of their Offspring.
Author(s):
Chidera Nneji Obiegbusi*
Women with Poly Cystic Ovarian Syndrome (PCOS) who become pregnant
have a high risk of metabolic and endocrine disorders that predispose them
to complications such as gestational diabetes, miscarriage, small for
gestational age infants, and neonates with an increased risk of admission to
a neonatal intensive care unit, among others. Metformin, the first line
treatment for type 2 diabetes, provides an attractive therapeutic option for
managing such patients due to its benefits on various metabolic aspects.
Using metformin to treat women with PCOS during pregnancy has yielded
favorable pregnancy outcomes. However, some recent reports associate
prenatal exposure to metformin with obesity in children. Additionally,
several animals’ studies associate metformin use in pregnancy to sexual and
fertility problems in the offspring, which highlights the nee.. Read More»
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