Background: Combination of nano crystalline hydroxyapatite with Advanced Platelet Rich Fibrin (A-PRF) and Hydroxyapatite reinforced Beta Tri-Calcium Phosphate (HA+β-TCP) with A-PRF for the treatment of infrabony defect will be effective in reduction of probing pocket depth, gain in clinical attachment level and defect fill. Aim: To evaluate and compare the effectiveness of Nano crystalline hydroxyapatite with Advanced Platelet Rich Fibrin (A-PRF) and Hydroxyapatite reinforced Beta Tri-Calcium Phosphate (HA+β-TCP) with A-PRF in the treatment of human infrabony defects clinically and radio graphically using Cone Beam Computed Tomography (CBCT). Methods: 28 defects will be randomly divided into test and control group consisting of 14 defects in each. Test group will be treated by nano crystalline hydroxyapatite particles with A-PRF and control will be treated by hydroxyapatite reinforced beta tri-calcuim phosphate with A-PRF. Primary outcomes will be radiographic bone fill and Secondary outcomes will be CAL gain and PPD reduction. The Clinical parameters will be recorded at baseline and 6 month postoperatively. Results: The Standard Deviation and Mean (Mean ± SD) values will be calculated for PI and papillary bleeding index and also for all clinical parameters including RGML, RAL, PPD, WKG and GR. To co-relate the data from base line to six months of each group students paired t-test will be used. To compare two groups at the day of surgery and six months student’s unpaired t-test will be used. Nano crystalline hydroxyapatite particles with A-PRF will result in significantly greater CAL gain, PPD reduction and radiographic bone fill at 6 months when compared to Hydroxyapatite reinforced Beta tri-calcuim phosphate with A-PRF. Conclusion: Combination of Nano crystalline hydroxyapatite particles with A-PRF will be effective in the treatment of infrabony defects. Nano crystalline hydroxyapatite particles with A-PRF will have significantly greater outcome as compared to Hydroxyapatite reinforced Beta tri-calcium phosphate with A-PRF.
Select your language of interest to view the total content in your interested language
Annals of Medical and Health Sciences Research received 24805 citations as per google scholar report
The Annals of Medical and Health Sciences Research is a monthly multidisciplinary medical journal.