Background: Choleliathisis, in patients with renal transplantation, carries high risk of complications. We, at our institute, perform prophylactic cholecystectomy for aymptomatic gallstones in patients with renal transplantation. Aim: To present our experience of laparoscopic cholecystectomy in patients with kidney transplantation. Subjects and Methods: Data, in the form of, demographics, medications used, indication of transplantation, manifestation of gallstones, operative findings, duration of hospitalization, and postâoperative complications were obtained and results were analyzed. briefly summarize details of statistics including the soft ware used. Results: Twenty patients have undergone laparoscopic cholecystectomy. All patients were admitted on the day of surgery. Immunosuppression regimen was not modified during hospitalization. Indications of cholecystectomy were biliary colic (8/20 patients, 40%), acute cholecystitis (8/20 patients, 40%), asymptomatic gallstones (3/20 patients, 15%), and obstructive jaundice (1/20 patients, 5%). Laparoscopic cholecystectomy was uneventful in all cases. Postâoperative complications were nausea and vomiting in two patients and port site infection in one patient. Conclusion: Laparoscopic cholecystectomy, when performed in renal transplant patients, is a safe procedure.