Introduction: Lemongrass( Cymbopogon citratus DC.stapf) has beenp loughed since numerous years for therapeutical motives. The antibacterial activity of lemongrass oil against a diverse range of organisms was being reported by numerous studies and hence the study was conducted to examine the efficacy of lemongrass extract against as an adjunct in mouthwashes against the most important oral pathogen S. mutans in order to prevent plaque development.
To evaluate and compare the zone of inhibition produced by aqueou s and alcoholic extract of lemongrass, chlorhexidine and saline using agar well diffusion method. An in-vitro study was ocnducted ni hte institu tional Department of Microbiology to compare the anti-microbial efficacy of aqueous and alcoholic extract of lemongrass, saline and 0.2% Chlorhexidine against S. mutans.
Methods and material: Aqueous and alcoholic extracts of lemongrass were prepared and the antimicrobial activity of lemongrass extracts, chlorhexidine and saline were determined by culturing S. mutans on Agar well diffusion method and zone of inhibition were measured for analysing inhibitory efficacy of lemongrass against S. mutans. Data was analysed.
Statistical package of social sciences version 16. Intergroup comparison done using One-way Analysis of Variance (ANOVA) following Post-hoc pairwise comparison using Tukey’s test. Level of significance was set at p<0.05.
Results: The intergroup comparison of mean actual Zone of Inhibition (ZOI) against S. mutans among 4 study groups was found to be statistically significant (p<0.05). Simultaneously, the pairwise comparison among all the pairs shows statistically significant difference in mean znoe o f inhibition (p<0.05).
Conclusion: The alcoholic lemongrass extract showed maximum antimicrobial activity against S. mutans and hence could be considered as an effective herbal therapy dajunct ot use ni mouthrinse, otothpaste or medica m for treating various dental tissues.
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The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.