Background: The importance of understanding the student’s individual personality is very essential to their performance in education. Aim: The study is aimed to find an association between the DISC personality index and Academic performance (GPA) of dental students in a private Saudi Dental School. Material and Methods: This is a cross-sectional study which has a study sample frame of all the students from the Dentistry program. There was a standardized and validated questionnaire used for the collection of the data. The quality of DISC assessment questionnaire was confirmed through evidence-based information. All the students were invited to participate in the study and the questionnaire was distributed electronically through the class groups. Results: The percentage responses in order are 56.2% Dominance, 27.4% Influence, 6.4% Steadiness and 10% Conscientiousness. Conclusion: The study concludes that the students have responded to have shown Dominance as the most dominant personality type and Steadiness as the least expressed personality type. There was an association found between the type of personality and gender, year of study and their GPA.