Comparison of Different Spirometry Reference Equations in Predicting Lung Function in Sri Lankan School Children

Author(s): G Liyanage*, BDW Jayamanne and Aaqiff M

Background: In Sri Lanka, for interpretation of spirometry, we often refer South Indian reference values since we do not have normative values for children. Therefore, our aim was to derive Sri Lankan reference values and to compare that with non-Sri Lankan reference equations. Methods: Our reference equations for spirometry for children between 8-16 year olds derived from socio-demographically representative sample “healthy” children. The technique of measurement complied with American Thoracic Society/European Respiratory Society 2005 recommendations. Those were compared with equations of Global Lung Function Initiative 2012 for South East Asians and South Indian values. Results: Measured values of this study are best matched to values from South Indian children. However, values of GLI 2012 are considerably higher than the observed values of the study sample. Conclusions: Observations suggest that reference equations should be derived from the same or comparable populations for which the reference values are to be used.

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