Background/Purpose: This study was to investigate the effectiveness of pilates mat exercises as compared with motor control exercises in treatment of nonspecific acute low back pain. Methods: A quasi experimental study was conducted at THQ hospital, Ahmadpur East, Punjab, Pakistan. From July 2020 till December 2020. A convenient sample 20 patients were recruited with diagnosis of non-specific low back pain. Patients were divided in to 2 groups of 10 patients in each group. Pilates Exercise Group (n=10) received 30 minutes training session, 3 days a week for 4 weeks and motor control exercise group (n=10) received motor control training. The outcome measure was Numeric Pain Rating Scale (NPRS) and Roland- Morris Disability Questionnaire (RMQ). Data was analysed through SPSS 23. Results: The data was found to be normally distributed. Pilates exercise training group showed better effects as compared to motor control exercise group in terms of NPRS (p<0.001) and RMQtest (p<0.001). Conclusion: It was concluded that pilates training group showed more significant effect on pain and reducing disability than motor control exercise group. Motor control training was also effective but pilates training group showed better effects.