Cytotoxic Effect of Three Different Silver Diamine Fluoride: An In-Vitro Study

Author(s): Sruthi S, Ganesh J* and Rajesh kumar S

Aim: Dental caries that are left untreated are the major problem in pediatric public health. For decades, Silver Diamine Fluoride (SDF) has been used to arrest caries in primary and permanent teeth. Thus, the aim of the study was to assess the cytotoxic effect of three different SDF’s.
Materials & Methods:To assess the cytotoxic potential, brine shrimp was cultured and were tested by adding 5 μL, 10 μL, 20 μL and 40 μL concentrations of Kedo, Kidz-e and Fagamin to it. The number of live nauplii’s present was noted after 24 hours.
Results: As the concentration increased, the cytotoxicity of the materials increased. The Kedo group showed 7 viable nauplii after 24 hours whereas, none were observed in the other two groups.
Conclusion: Kedo SDF showed less cytotoxic effect compared to Kidz-e and Fagamin and can be considered the best choice for arresting caries in primary and permanent teeth.


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