Objective: The objective of this study is to demonstrate the sustainability of changes in Central Macular thickness associated with Phacoemulsification surgery. Materials & Methods: Cohort study with 120 patient’s eyes was conducted from March 2020 to August 2020 at Riphah International University Lahore. Sampling technique was non probability convenient sampling technique. Inclusion criteria include all patients willing to undergone phacoemulsification with intraocular lens implant (phaco) surgery and having cataract with controlled diabetes and hypertension. Exclusion criteria include all patients who didn’t agree to undergone phaco surgery. Patients with any other ocular pathology were excluded from the study. Refractive status objectively assessed by Canon Autorefractor and Heine retinoscope. Vision was assessed at six (06) meters of distance using Snellen chart and recorded using Snellen notation. Average reading of both methods was taken. The phacoemulsification was done using “OertliCataRhex 3” and foldable lens was implanted during the surgery. For the measurement of the macular thickness Zeiss Cirrus HD-OCT 500 model was used. All data entered and analyzed by SPSS 20 (Statistical Package for Social Sciences). Normality of quantitative data was checked by Shapiro Wilk test. Wilcoxon sign test was used for non-parametric data. P value <0.05 was taken as significant. Results: This study include 120 patient’s eyes that undergone successful phacoemulsification surgery. Macular thickness before the surgery was assessed and recorded on proforma. Mean macular thickness before surgery was 210 μm. After the surgery the macular thickness was recorded after 01 week and 04 weeks and the mean values were 243 μm and 207 μm respectively. The best corrected visual acuity after the surgery was 6/6 in 21%, 6/9 in 47% and 6/12 in 31% patients. There is significant difference between the macular thickness of before and after the phacosurgery (p=0.00). The macular thickness was decreases with the time and settled after 04 weeks of surgery. Conclusion: There is significant difference between the macular thickness before and after phaco surgery (p=0.000). The macular thickness is slightly raised after the surgery and observed to lower down after 04 week of surgery.