Malnutrition affects more than 95.9% of population in developing nations, and it has a big impact on children's health and their development and also associated with high morbidity impact and it is linked with changes in immunological-cytokines. The researchers needed to look at pro-in lammatory mediators in both healthy and underweight children. The goal of present study was to ind and compare the levels of pro-in lammatory cytokines in the control (healthy) and malnourished children. A total of 151 children were involved in this study, including 96 malnourished children and 55 healthy children of identical age and gender. The clinical, demographic, and plasma levels of Interleukin-1beta (IL-1beta) and 6, Tumor Necrosis Factor-alpha (TNF-alpha) and C-Reactive Protein (CRP) of these subjects were all evaluated using an ELISA kit. When compared to healthy children, malnourished children experienced a considerable reduction in weight and Weight-for-Age Z score (WAZ). Furthermore, the levels of serum interleukin-1 (IL-1) (0.10 vs. 0.05) and serum Interleukin-6 (IL-6) (pg/ml), (1.5 vs. 1.6), TNF-alpha (pg/ml) (1.7 vs.1.8), and CRP (mg/l) (0.7 vs. 1.0) were signi icantly higher in the malnourished group compared to the control group. Pro-in lammatory cytokines (IL-1, Interleukin-6 (IL-6), TNFalpha and CRP were found at higher concentrations in the blood of malnourished children.
Select your language of interest to view the total content in your interested language
Annals of Medical and Health Sciences Research received 20588 citations as per google scholar report
The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.