Obesity is reported to be associated with chronic low-grade inflammatory state, indicated by increased plasma level of C-reactive protein (CRP). Moreover, high prevalence of overweight and obesity among young Saudis is a serious health concern. Therefore, we designed this study to investigate the effect of obesity and perceived stress on plasma high sensitivity (hs)-CRP level in young Saudis. A total of 472 young healthy males (age, 19 ± 2) were categorized as underweight, normal, overweight and obese based on their body mass index. Plasma levels of hs-CRP levels were measured by nephlometry. In addition, the level of stress among the participants was determined using PSS-14 questionnaire. The results showed about 11% (53/472) underweight, 21% (100/472) overweight, 24% (114/472) obese and 43% (201/472) normal subjects. Mean values of hs-CRP obtained from these groups showed a rising trend being minimum in underweight while maximum in obese. The mean values of hs-CRP among different BMI categories was significantly different P=0.001. We also observed a significant Positive correlation between plasma hs-CRP level and Body mass index (BMI), Weight, Waist circumference (WC), Hip circumference and Waist Hip Ratio (WHR). Thirty percent (142/472) of our participants were found to be stressed. However, there was no significant difference in their hs-CRP levels. Pearson correlation between perceived stress scores, anthropometric parameters and hs-CRP levels were not significant. On the basis of these findings we can conclude that higher the BMI higher will be the level of plasmahs- CRP level representing presence of a state of low grade systemic inflammation in overweight and obese subjects, which might lead to cardiovascular events.
Select your language of interest to view the total content in your interested language
Annals of Medical and Health Sciences Research received 15898 citations as per google scholar report