Introduction: Knowledge, attitude, and practices (KAPs) are pillars in thefight against HIV/AIDS worldwide. It stands to be the very best helpful toolto evaluate and assess individual or community before implementingintervention program approaches. The study evaluates the knowledge,attitudes and practices on HIV, AIDS prevention and transmission amongcollege students in Pampanga, Philippines. Materials and Methods: This is across-sectional, descriptive research method utilising a self-administeredquestionnaire among 565 college students aged 18-24 in three selectedhigher educational institutions in Pampanga, Philippines; The statisticalanalyses included univariate analyses, frequency, percentages, mean andStandard Deviation (SD) or median, interquartile range (IQR) and SPSS. Chi-square test of independence for the association.