Background: Weak vaccine delivery systems and poor immunization coverage have been perennial problems in Nigeria. This work was designed to assess the effectiveness of vaccine delivery in a Community Cottage Hospital in the Niger Delta area of Nigeria by determining immunization completion and drop-out rates among infants registered in the facility from January 2014 to January 2015. Methodology: Immunization records at the centre were examined for completion of immunization schedule and drop-outs. Mothers whose infants missed immunization were contacted by phone to ascertain the reason(s). Results: Three hundred and sixty-two infants were registered in the centre for immunization in the period. Of these 358 (98.80%) infants completed their schedule according to the Nigeria National Programme on Immunization. The BCG to measles drop-out rate was 0.55%, DPTI to DPT3 0.00%, and DPTI to measles 0.55%. Conclusion: Integration of Primary Health Care Services, community participation, staff motivation through private sector principles and regular power supply may be some of the factors engendering this salutary state. This can serve as a model for similar facilities in the region.