The issue of food security is a complex one in both developed and developing countries, where proteins source from animals such as fish and fish products are generally regarded as high risk and unwholesome commodities with respect to pathogen contents, availability of natural toxins and other possible contaminants, especially when raw or undercooked fish and fish products are consumed, also the use of adulterants reduction in economic growth. Fish deterioration by microbial spoilage during the harvesting, transportation, storage, and poor hygienic maintenance is a global problem regarding food safety and economic impact and it is a major concern for seafood consumers. The possible sources of these contaminants are due to the unhygienic manner of handling fish or from marine pollution that could contaminate fish. This implies that these fish are viable sources of various diseases. Some of these diseases could spread and acquire epidemic status which could pose and even death, especially in children. There is a need to educate for good production practices among food processors and food vendors. It is expedient that good hygienic practices should be observed at the market. Also, prevention of marine water pollution which could pollute fish and marine animals must be applied.