This article examines physical fitness status, motivation for physical exercise, and difficulties encountered in Physical Education (PE) classes by visually impaired students at special schools in Ho Chi Minh City, Vietnam. The study used interview methods, sports measurement, and SPSS 20.0 software to analyze the results of this study. Conducted research on 52 visually impaired students 11-14 years old. The research results show that the superiority of "height" and the "heart function" index of impaired students are good to be better than the average height, heart function, Vietnamese students of the same age, but inferior in physical factors force. At the same time, the study also pointed out the positive factors, the visually impaired students' interest and their difficulties in PE lessons.