Background: The severity of lung involvement associated with SARS-CoV-2 infection levels from lack of symptoms or slight pneumonia (in 81%) to excessive disease-associated hypoxia (seen in 14%), a critical disease associated with shock, respiration failure, and multi-organ failure (in 5%) or death (2.3%). Aim: This work aims to determine the prevalence of clinical and radiological manifestations among children and adolescents COVID-19 patients. Materials and Methods: A systematic search was performed over different medical databases to identify Pediatrics studies, which studied the outcome of COVID-19 infection in children and adolescents. Using the meta-analysis process, either with fixed or random-effects models, we conducted a meta-analysis on the prevalence of clinical manifestations (e.g., fever, nasal congestion, cough, dyspnea, abdominal pain, diarrhea, and critical cases), as primary outcomes, and on radiological manifestations (e.g., CT involvement – ground-glass opacities), as a secondary outcome. pooled prevalence of abdominal pain = 9.6%, pooled prevalence of critical cases = 7.7% Results: Eight studies were identified involving 682 patients. The meta-analysis process revealed a pooled prevalence of fever = 61.1%, a pooled prevalence of nasal congestion = 8%, pooled prevalence of cough = 49.7%, pooled prevalence of dyspnea = 21.4%, pooled prevalence of diarrhea = 13.3%, pooled prevalence of critical cases = 7.7%. Concerning the secondary outcome measures, the pooled prevalence of CT involvement = 41.6%. Conclusion: To conclude, COVID-19 disease cause different manifestations in children such as fever and respiratory symptoms such as cough and dyspnea, organizing pneumonia and decreased pulmonary function.
Select your language of interest to view the total content in your interested language
Annals of Medical and Health Sciences Research received 20588 citations as per google scholar report
The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.