Prevalence of COPD Concerning Severity of COVID-19 Infection: A Short Systematic Review and Metaanalysis

Author(s): Yousef M Alluhaymid*, Fahad Saleh Almutairi, Walaa Saleh Alnakhlie, Zahra Malik Alsadiq, Ghanem Gharbi Alanazi, Rifal Saleh Alqaan, Shahd Yousef Badr, Eman Mazyad Alruwaili, Reham Ahmedfouad Saber, Ghada Tareq Kersh and Abdulqader Ali Alfaifi

Background: Concerning COVID-19, levels of angiotensin-converting enzyme 2 (ACE2), the said host receptor of the virus responsible for COVID-19 (intense acute respiratory syndrome coronavirus 2; SARS-CoV-2), were located to be elevated in patients with COPD. But, early character COVID-19 studies have not always pronounced a drastically better fee of severe disease in COPD sufferers. Aim: This work aims to determine the prevalence of COPD concerning the severity of COVID-19 infection. Materials and Methods: A systematic search was performed over different medical databases to identify Internal Medicine studies, which studied the outcome of the COPD group versus the Non-COPD group of COVID-19 patients. Using the metaanalysis process, either with fixed or random-effects models, we conducted a metaanalysis on the prevalence of severe cases as a primary outcome, and on mortality rate as a secondary outcome. Results: Eleven studies were identified involving 146666 patients, 2764 in the COPD group, and 143902 in the Non-COPD group. The metaanalysis process revealed that the pooled prevalence of severity among COVID-19 patients was (28.7%), and there is a significant increase in COVID-19 severe cases in the COPD group (OR=3.46, P=0.042). The pooled mortality rate among COVID-19 patients was (16.7%), and there is a highly significant increase in mortality in COPD group (OR=3.75, P<0.001). Conclusion: To conclude, COVID-19 is an emerging disease all over the world and spreading at an unpredicted rate, resulting in significant influences on global economies and public health. The present review assessed the risk factors related to the outcomes of SARS-CoV-2 infections which were included old age, male gender, and obesity, associated co-morbidities in COPD, which increase the mortality and severity of COVID-19. mp3download.link Best YouTube to MP3 converter. Download MP3 from YouTube for Free. one would honestly have expected more on the track https://www.mp3-go.net Download Mp3 songs for free Given the legendary pedigree of the man behind the sound downloadmp3-gratis.biz Download mp3 songs online at Mp3 Converter, watch high quality online music videos download-mp3gratis.me watch and download free songs of the highest quality. Listen to songs online here comfortably without any annoying advertisements. metrolagu.site Easy to use and free MP3 downloader. YouTube To MP3 download in seconds using the best YouTube to MP3 converter. YouTube To Mp3 Get the latest song by simply typing the latest artist or song title in the Search menu. Mp3 file format with 128 - 320 Kbps bitrate converted from YouTube videos. read at this blog All those artist performances are still available on YouTube today find more here


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