Objectives: Mentally challenged individuals are faced with many challenges in understanding and maintain their health and are particularly vulnerable to having unmet health care needs. Prosthetic status of these individuals has received a very little attention and there is paucity of information about their prosthetic status and prosthetic needs. A cross sectional study was conducted to assess the prosthetic status and prosthetic needs of mentally challenged individuals attending special schools in Nasik district, Maharashtra, India. Subjects and methods: On the basis of convenient nonprobability sampling technique. All the mentally challenged individuals residing at special school of Nasik district was examined to assess for prosthetic status and prosthetic needs. Data was evaluated by using Statistical Package for Social Science version 20. Data comparison was done by applying Chi‑square test. Results: A total 272 subjects were examined. Out of that 201 were male subjects and 71 were female subjects. Among 272 study subjects, 20.56% of the subjects were having prosthesis. 73.16% of study subjects were having prosthetic needs, that includes single and multiple unit prosthesis. The need for single unit prosthesis (46.31%) was higher than multiple unit prosthesis (26.83%). Female subjects were reported higher prosthetic needs (94.28%) than male subjects (66.58%) in all groups, but the difference was not statistically significant. Conclusion: The results of the study shows that, there was high percentage of unfulfilled prosthetic needs among mentally challenge individuals attending in special school in Nasik district A strong deficit was seen in between the prosthetic needs and prosthetic status.