Research Article
Impact of Family Background of Cardio-Metabolic
Disorders and Associated Risk Factors on Total
Adiponectin in Children
Author(s):
Thomas Ulasi, Henry Okpara, Ezinne Nwaneli, Ogochukwu Ofiaeli, Chijioke Ezeudu and John Chukwuka
Background: Adiponectin is a novel hormone with unique biologic functions. Objective: Evaluating adiponectinpattern among children with a family history of cardio-metabolic diseases and risk factors may shed insight into the pathophysiologic mechanism behind these diseases among those at risk. Methods: 101 healthy children, aged 4 to 12 years, were enrolled in this study. Family history of diabetes, hypertension, obesity in both first and second degree relatives were established using Intervieweradministered questionnaires to the study participants’ caregivers. Other data collated include the smoking history, occupation and highest educational attainment of the caregivers and birth weight of the study participants. Venous blood samples were assayed foradiponectin using ELISA kits. Data were analyzed using SPSS softwa.. Read More»
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