Research Article
Risk Factors Associated with Severe Exacerbation in Non-Smoking COPD Patients in Primary Care: A Retrospective Observational Study
Author(s):
Josep Montserrat Capdevila*, Pilar Vaqué Castilla, Jennyfer Jiménez Díaz, Joan Deniel-Rosanas, Araceli Fuentes Botargues and Eugeni Paredes Costa
Background: Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality worldwide. While smoking is the main risk factor, a significant subset of COPD patients are non-smokers. The clinical features and exacerbation risk factors in this population remain understudied, especially in primary care. Objective: To identify risk factors associated with severe exacerbations in non-smoking patients with COPD in a real-world primary care cohort. Methods: We conducted a retrospective cohort study using anonymized data from 2,376 patients diagnosed with COPD in a Spanish primary care setting. Patients were classified according to their smoking status; only non-smokers (n=1,582) were included in the analysis. Severe exacerbation was defined as hospitalization or emergency department visits due to COPD worsening. We performed bivariate analyses and multivariate logis.. Read More»
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