Letter to the Editor
Serum Adiponectin Levels are Associated with Microcirculatory Function, but not with Coronary Artery Disease in the Young
Author(s):
De Lorenzo A*, Moreira ASB, Guimaraes E, Oliveira GMM, Maia E and Tibirica EV
Adiponectin is secreted in mature adipocytes, has a role in diabetes and obesity and has been studied in coronary artery disease (CAD), considered cardioprotective, what is nonetheless controversial. The assessment of systemic microvascular reactivity is useful for the evaluation of cardiovascular diseases, and laser speckle contrast imaging (LSCI) is an innovative approach, using the cutaneous microcirculation as a representative vascular bed.[4] We evaluated serum adiponectin levels in early-onset CAD (EOCAD) patients and age-matched controls, as well as their association with microvascular function assessed by LSCI. EOCAD was defined as any obstruction ≥50% on coronary angiography, prior myocardial infarction, or myocardial revascularization in patients ≤45 years. Patients with acute coronary syndromes or interventions for <6 months were not in.. Read More»
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The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.