Research Article    
                                                Lumbosacral Chordomas: The Enigmatic and Dreaded Entity 
                                                Author(s):
                        Mir Younis Ali, Mohsin Fayaz* and Abdul Rashid Bhat                        
                                                
                        
                        Introduction: Primary tumours of the spine are rare, accounting for less than 5% of all osseous
  neoplasms and less than 0.2% of all cancers. Among all primary tumours of the spine, the
  incidence of primary malignant tumours varies between 32% and 71%. The most common
  primary malignant tumours of the spine are chordoma and sacral sarcomas like chondrosarcoma,
  osteosarcoma and Ewing sarcoma. Chordoma is a slow-growing, locally aggressive neoplasm
  of bone which arises from embryonic remnants of the notochord, with an overall incidence of
  0.08 per 100,000 individuals accounting for 40% of all primary sacral tumours. The tumour has
  a delicate pseudo capsule, in which satellite lesions and occult extension are frequent. Hence,
  local recurrence is expected due to failure to achieve negative surgical margins. Chordomas
  are insensitive to chemotherap.. Read More»
                                                
                                              
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