Neelesh Gupta

Department of Neurology, National Institute of Mental Health and Neurosciences, Karnataka, India


  • Original Article   
    Snakebite, Antivenom and Mitochondrial Toxicity
    Author(s): Sadanandavalli Retnaswami Chandra*, Thomas Gregor Issac and Neelesh Gupta

    Background: Snake bites are common in underdeveloped countries and produces generally cardiac, renal and neuromuscular complications. Common side effect of antivenom is anaphylaxis. Snake poison is the most complex natural poison which acts on the victim by the multiple components present in it. Apart from supportive treatment polyvalent antivenom is used in treatment. Neither the snake venom nor the antivenom is reported to have mitochondrial toxicity so far in literature. Subject and Methods: A 10-year-old male child presented with cardiovascular collapse following snake bite and treated with polyvalent antivenom. Following a brief period of recovery, patient presented with features of acute mitochondrial encephalopathy which was confirmed by T2 changes and lactate peak in MR spectroscopy. Child made complete recovery wi.. Read More»

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