AMHSR

Otamiri C

Department of Pharmacology and Therapeutics, University of Nigeria, Enugu Campus, Nigeria

Publications

  • Original Article   
    Petroleum Products Induced- Cardiac Enzymes and Histological Changes in Wistar Rat Model: Is there any Implications for Cardiovascular Disease in Nigeria?
    Author(s): Anakwue RC and Otamiri C

    Background: Some of the causes of cardiovascular diseases (CVDs) which have continued to increase in prevalence worldwide are unknown. It is known that petroleum products are abused widely in Nigeria. Objectives: We sort to find out if exposure of rats to petroleum products in the same manner that people inhale these products could cause significant cardiac toxicity. Methods: Our study involved exposing wistar rats to fumes of petroleum products. Group 1 was the control, groups 2 and 3 were exposed to varying duration of inhaled kerosene and groups 4 and 5 were exposed to varying duration of petrol. Blood samples were collected by orbital puncture and complete necropsy of the heart was performed and gross lesions recorded in all the animals. Results: The result showed increased serum level.. Read More»

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