Original Article
Molecular Epidemiology of Mycobacterium Tuberculosis Strains in the North‑West and West of Iran
Author(s):
Sahebi L, Ansarin K*, Hoffner S, Farajnia S, Seyyedi M, Khalili M and Monfaredan A
Background: Identifying Mycobacterium tuberculosis (MTB) transmission type is a key step in the control of this disease. Aim: This study aimed to determine the path and transmission type of MTB and the insertion sequence IS6110 band number and verify their relationship to demographic and clinical risk factors. Subjects and Methods: In this crossâÂÃ?Â?ÂÃ?Â?sectional study, 64 MTB patients from three border provinces of Iran were selected after full clinical history and physical evaluation design. The drug susceptibility testing was carried out using the standard proportion technique on sputum samples. Isolates tested with restriction fragment length polymorphism technique used IS6110. Results: Recent transmission of disease was 33/50 (66%) based on clustering rate. The IS6110 band number had a significant relationship with drug resistance detected in proportion method.. Read More»
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