Reviews
Incidence of Malignancies Spondyloarthritis Patients Treated with Biologics vs Non-Biologics: Systematic Review and Meta-analysis
Author(s):
Thekra Ali Alghamdi*, Lama Morshed Alharbi, Atheer Musfer Alzahrani, Reem Mohammed Alqahtani, Rahaf Fouad Wajdi, Sarah Abdullah Alqarni, Walaa Faisal Alahmadi, Shaima Humied Alharbi, Ohoud Mousa Zubani and Suhailah Eid Alaklouk
Background: Biologic therapies have all demonstrated efficacy inside the treatment of AS. however, some patients do not reply to remedy (i.e., number one treatment failure) or enjoy diminished efficacy over the years (i.e., secondary treatment failure), while others experience side effects necessitating treatment discontinuation e.g. (incidence of malignancies). Aim: This work aims to assess the incidence of malignancies in spondyloarthritis (SpA) patients treated with biologics. Materials and Methods: A systematic search was performed over different medical databases to identify Internal Medicine studies, which studied the outcome of the Biologics group versus the Non-biologics group of spondyloarthritis (SpA) patients. Using the meta-analysis process, either with fixed or random-effects models, we condu.. Read More»