Aim & Objective: This study aimed to evaluate the efficacy of anesthesia obtained with a Classical inferior dental nerve block compared with the Gow-Gates mandibular nerve block for posterior dentoalveolar surgical procedures. Material & Methods: 100 Patients requiring mandibular posterior dentoalveolar surgical procedure under local anesthesia were randomly selected from the outpatient department. These patients were divided equally into two groups of 50 each with age range of 18 to 56 years. In group A, local anesthetic solution administered by standard technique to achieve mandibular anesthesia while in group B the Gow-Gate technique was used. The statistical analysis was done using SPSS (Statistical Package for Social Sciences) Version 15.0 statistical Analysis Software. The values were represented in Number (%) and Mean ± SD. Result: The patients in group B showed no complications during or after injection, time of onset on anesthesia and complete recovery from anesthesia were found more in group B. Most of the patients were highly satisfied with Gow-Gates nerve block. Conclusion: Gow- Gates technique is superior to inferior alveolar nerve block . It requires expertise and higher skill which one develops with practise.