Introduction: Infertility is one of the problems faced by many couples in society and one of the treatment methods that are being performed in our country for many years is donation of gametes. Considering the importance of maintaining the physical and mental health standards for donors and the lack of a comprehensive study on the personality characteristics of donors in our country, we decided to help solve these challenges with a research. Material and Methods: In this cross-sectional study, by attending the Royan Institute, after giving necessary explanations to all those who were attending that center to donate egg, the TCI was filled out by those who volunteered. Data were analyzed using SPSS 21 software. Results: The highest motivations for egg donation were stated to be financial issues (48%). In the study of personality characteristics, there was a significant difference between dimensions of self-transcendence, self-directed, persistence, avoidance of harm, and cooperation between these individuals and control group. There was also a significant difference between the two groups regarding history of attending a psychiatrist, history of drug treatment, and history of psychiatric counseling. Conclusion: In this study, egg donors were more cooperative, more persistent and more self-directed. In terms of innovativeness and reliance on rewards, there was no significant difference with the control group, but in the self-transcendence dimension and avoidance of harm, they obtained fewer score than the control group.