Introduction: Demirjian’s dental maturity scores are widely used to assess dental maturity and estimate age. Various authors revised Demirjian’s method by adapting Demirjian’s stages and proposed new data for age estimation. The present study aimed to assess the age using original and modified Demirjian methods from the reference data and also to correlate dental age with chronological age. Materials and methods: In the target sample of 660 dental radiographs of age 6-16.99 years, seven mandibular permanent teeth (Central incisor I1 to Second molar M2) were assessed and dental age was calculated using four maturity scales and ten methods that use data for individual teeth. The mean difference between dental age (DA) and chronological age (CA) was calculated as well as other measures of accuracy such as mean obsolute difference (MAD), percentage aged to within six months and to within 10% of age. Results: The method that performed best was the dental maturity scale of Willems I et al .(highest percentage of individual aged to within 0.5 years of real age) with MAD of 1 year, followed by Original Demirjian method with MAD of 1.06 years and Willems II method with MAD of 1.1 years. Conclusion: The present study showed that original Demirjian’s method was found to be highly accurate followed by Willems I method. Thirdly, Willems II method was better followed by Chaillet et al. method. All the fourteen methods assessed were found to reliable for age estimation in South Indians.