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Ahed J Khatib

Department of Medicine and Critical Care, Academician Secretary of Sociology, Irbid, Jordan


  • Review   
    Immunohistochemical Analysis of Lung Cancer: Review Article
    Author(s): Ahed J Khatib* and Marwa Yousry A. Mohamed

    Lung cancer is one of the most prevalent cancers, but it is usually lately discovered. The main objective of this study was to review the literature about the use of biomarkers applying immunohistochemistry on tissues. Reviewing literature showed the need to use biomarkers to help in both diagnosing and assessing the clinical status of lung cancer. To choose the best course of treatment, it is essential to diagnose and distinguish Lung Adenocarcinoma (LUAD) from Lung Squamous Cell Carcinoma (LUSC), as recent targeted medicines demand precise subtyping Nonsmall-cell Lung Cancer (NSCLCs). Several biomarkers that could be used to distinguish between LUAD and LUSC, but they are less sensitive, specific, and clinically useful. LUSC expressed more SPATS2 and CLCA2 than LUAD. The expression of ST6GALNAC1 and Adipophilin was hfigher fin LUAD than LUSC (P 0.001). The CLCA2, SPATS2, ST6GALNAC1,.. Read More»

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Annals of Medical and Health Sciences Research The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.
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