amhsr-open access medicla research journals

Iyiola Sina

Department of Medical Laboratory Science (Histopathology Unit) college of Basic and Health Science, Achievers University, Owo, Ondo State, Nigeria


  • Research Article   

    Author(s): Ekundina Victor Olukayode*, Alabi Gloria Oluwagbenro, Ajiboye Oluwaseunfunmi, Awopetu Ayodele Victoria and Iyiola Sina

    Background: ATM is a Phosphatidylinositol-3-Kinase–Related Kinase(PIKKs), belonging to a family of serine/threonine kinases that also contains DNA-Dependent Protein Kinase (DNA-PK), which plays a role in the DNA Double-Strand Break (DSB) repair pathway of Non-Homologous End Joining (NHEJ), and Mammalian Target of Rapamycin (mTOR), a key autophagy regulator. ATM recognizes and amplifies the signal generated by double strand break, upon activation, CHK2 are released from chromatin and halt cell cycle progression to allow repair. The aim was to study the mutation of Ataxia telangiectasia gene and Chek2 gene in a malignant and benign breast lesion. There is a hitch in the comprehension of the concept of carcinogenesis thus, changes that occur to genes which cause cells to malfunction, causing them to grow and divide when they should not is not well understood. Materials and Methods:.. Read More»

Select your language of interest to view the total content in your interested language

Awards Nomination
20+ Million Readerbase
Abstracted/Indexed in

  • Include Baidu Scholar
  • CNKI (China National Knowledge Infrastructure)
  • EBSCO Publishing's Electronic Databases
  • Exlibris – Primo Central
  • Google Scholar
  • Hinari
  • Infotrieve
  • National Science Library
  • ProQuest
  • TdNet
  • African Index Medicus
Annals of Medical and Health Sciences Research The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.
Submit your Manuscript