Reviews
Detrusor External Sphincter Dyssynergia (DESD) and Botulinum Toxin A (BoNT-A): Meta-analysis of Efficacy
Author(s):
Masoud B Alshammari, Abdulla J Alkhalifa, Mohammed M AlMutairi, Abdulmalik A Alkhamis, Abdulrahman A Almulhim, Alaa Kh Alshammari, Fatimah M Alhaddad, Zahra H Alobaidan, Ghadeer A Altaqaq, Sarah A Aljishi and Mohannad A Alsulami
Botulinum toxin A injection into the detrusor can reduce detrusor contractility, improve bladder compliance, and resume urinary continence. While a urethral injection of BoNT-A may reduce the urethral resistance and facilitate bladder emptying reducing postvoid residual (PVR) and frequent urinary tract infections. This work aims to provide cumulative data about the efficacy of Botulinum Toxin A (BoNT-A) in treating patients with Detrusor External Sphincter Dyssynergia (DESD). A systematic search was performed of PubMed, Cochrane library Ovid, Scopus & Google scholar to identify Urology RCTs, clinical trials, and comparative studies, which studied the outcome of Baseline assessment versus Follow-up assessment of DESD patients. A meta-analysis was done using fixed and random-effect methods. T.. Read More»
Select your language of interest to view the total content in your interested language
Annals of Medical and Health Sciences Research received 20588 citations as per google scholar report