Mohsen Saeidi

Faculty of Medicine, Department of Stem Cell Research Center, Golestan University, Medical Sciences, Gorgan, Golestan province, Iran

Publications

  • Original Article   
    Genetic Polymorphism of CYP2C9 among Sistani Ethnic Group in Gorgan
    Author(s): Mohsen Saeidi, Aman Mohammad Gharanjik and Abdoljalal Marjani*

    Background: Cytochrome P450 2C9 (CYP2C9) is involved in metabolism of many important drugs and its genotype variations is thought to affect drug efficacy and the treatment process. Aim: The aim of this study was to assess the distribution of CYP2C9 allele and genotypic variants in Sistani ethnic group, living in Gorgan, South East of Caspian Sea and North East of Iran. Subjects and Methods: This study included 140 Sistani, referred to the health center of Gorgan. CYP2C9 genotyping was carried out by Polymerase Chain Reaction -Restriction Fragment Length Polymorphism technique. Results: The allele frequency of CYP2C9*1, CYP2C9*2 and CYP2C9*3 was 76.1%, 16.1% and 7.8%, respectively. The frequency of CYP2C9*1/*1,CYP2C9*1/*2, CYP2C9*1/*3, CYP2C9*2/*2, CYP2C9*2/*3 and CYP2C9*3/*3 genotypes was .. Read More»

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