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Ucheya RE

Department of Anatomy, School of Basic Medical Sciences, College of Medical Sciences, University of Benin, Benin City, Edo State, Nigeria


  • Original Article   
    Histochemical Studies of the Effects of Monosodium Glutamate on the Liver of Adult Wistar Rats
    Author(s): Eweka AO*, Igbigbi PS and Ucheya RE

    Background: Monosodium glutamate (MSG) is a commonly used food additive and there is growing concern that excitotoxins such as MSG play a critical role in the development of several hepatic disorders. Objectives: The histochemical effect of monosodium glutamate was investigated on the liver of adult Wistar rats. Methods: Adult male Wistar rats (n = 24), with an average weight of 230 g were randomly assigned into two treatment groups, (A & B) (n=16) and Control (C) (n=8). The rats in the treatment groups (A & B) received 0.04mg/kg and 0.08mg/kg of monosodium glutamate thoroughly mixed with the grower’s mash, respectively on a daily basis for forty-two days. The 0.04mg/kg and 0.08mg/kg monosodium glutamate doses were chosen and extrapolated in this experiment based on the previous work done with the additive. The control group (C) received equal amount of f.. Read More»

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Annals of Medical and Health Sciences Research The Annals of Medical and Health Sciences Research is a bi-monthly multidisciplinary medical journal.
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