Ugwu Malachy

Department of Pharmaceutical Microbiology and Biotechnology, Faculty of Pharmaceutical Sciences, Nnamdi Azikiwe University, Awka, P.M.B 5025, Anambra State, Nigeria

Publications

• Original Article   
  Detection of Metallo-β-lactamase (MBL) among Carbapenem-Resistant Gram-Negative Bacteria from Rectal Swabs of Cow and Cloacae Swabs of Poultry Birds
  Author(s): Ejikeugwu Chika*, Esimone Charles, Iroha Ifeanyichukwu, Okonkwo Eucharia C, Gugu Thaddeus, Oli Angus N, Ugwu Malachy, Ezeador Chika and Moses N Ikegbunam
  
  Background: Metallo-β-lactamases (MBLs) are carbapenem-hydrolyzing enzymes that give Gram-negative bacteria the exceptional ability to resist the antimicrobial onslaught of the carbapenems such as imipenem and meropenem. MBL-producing Gram-negative bacteria exist in the community and hospital environment and they put their use of the carbapenems at risk. Aim: This study phenotypically evaluated the prevalence of MBL-positive bacteria from carbapenem resistant Gram-negative bacteria of abattoir and poultry origin. Materials and methods: A total of 370 environmental samples comprising samples from abattoir tables, anal swabs of cow and cloacae swab samples of poultry birds were bacteriologically analyzed for the isolation of carbapenem Gram-negative bacteria. Antibiogram was determined by.. Read More»