Nasreen R Jber

Chemistry Department, College of Science, Al-Nahrain University, Baghdad, Iraq

Publications

• Case Reports   
  Trilogy-Function Thiadiazole-Triazole-Pyridine Derivatives as Anticancer Activity
  Author(s): Nasreen R Jber* and Mehdi S Shihab
  
  1-Methyl-4-(6-(subsitutedphenyl)-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazol-3-yl)- alkylpyridinium was synthesized in this study. The 4-Amino-5-pyridin-4-yl-4H-(1,2,4) triazole-3-thiol was combined with substituted phenacyl bromide in a condensation reaction to produce 4-Amino-5-pyridin-4-yl-4H-(1,2,4)triazole-3-thiol. 1-Methyl-4- (6-(substitutedphenyl)-(1,2,4)triazolo(3,4-b)(1,3,4)thiadiazol-3-yl)pyridinium was alkylated with three distinct alkyl bromides. The anticancer effects of the produced triazolo (3,4-b)(1,3,4)thaidiazole pyridine derivatives were investigated using FTIR and 1H-NMR, and some compounds in the series showed promising anti-cancer activity when compared to standard medications... Read More»
  10.54608.annalsmedical.2022.25